Combination therapy for retinopathy of prematurity

Toy et al. described 17 infants (33 eyes) who were treated with intravitreal bevacizumab (0.625 mg) injection for type 1 retinopathy of prematurity (ROP) followed by subsequent exam under anesthesia and fluorescein angiography (FA) taken after 50 weeks of gestational age (1). All eyes had a “scalloped regression” pattern of the peripheral retina on FA. Recurrence or chronic vascular arrest based on FA findings were noted in 30 eyes (91%) for which secondary laser was added to areas of persistent non-perfusion.